Poisning Center - Pediatric On Call

4th Pediatric Infectious Diseases Conference

ISSN 0973 - 0958

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Rakesh Kumar, Binay Ranjan, Manjul Vijay Department of Pediatrics, Katihar medical college, Katiha...

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Drug

Treatment Details

Carbamates

They are derivatives of carbonic acid. They are marketed in the form of dusts or solutions, such as aldicarb {Temik}, aminocarb {Matacil}, apocarb {Baygon}, carbaryl {Sevin}, carbofuran {Furaxdan}.

Route : Absorption occurs through all routes

Mechanism of action : Absorption occurs through all routes
Carbamates differ toxicologically from organophoshphates in two ways:
1.They will spontaneously hydrolyse from the cholinesterase enzymatic site within 24 to 48 hours, whereas organophosphates will not
2.They do not effectively penetrate into central nervous system{CNS} and as such CNS toxicity is limited.
3.All other clinical manifestations are similar to organophosphates.

Treatment : •Antidote: Atropine blocks the muscarinic effects.
•Cholinesterase reactivators: Pralidoxime may diminish the severity of symptoms

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Should teicoplannin, colistin be used in case of neonatal sepsis where culture does not reveal any organism_?

No, it should be used only after drug sensitivity report

Yes, under guidance of an infectious disease expert

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